Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically focused entry point to rigorous research from Cochrane Reviews. They are designed to be actionable and to inform point of care decision making.
Below are recent cancer related Cochrane clinical questions, click on the links to view answers.
For people with non‐small cell lung cancer, what are the effects of adjunct chemotherapy? Jane Burch (PhD) and Sera Tort (MD) (on behalf of Cochrane Clinical Answers Editors). Cochrane Clinical Answers 2021. DOI: 10.1002/cca.3458.
For adults with non‐advanced colorectal cancer, what are the effects of physical activity? Agustín Ciapponi (MD, MSc) (on behalf of Cochrane Clinical Answers Editors). Cochrane Clinical Answers 2021. DOI: 10.1002/cca.3488.
For adults with locally advanced or metastatic soft tissue sarcoma receiving palliative care, how does doxorubicin monotherapy compare with doxorubicin‐based combination chemotherapy? Jane Burch (PhD) and Sera Tort (MD) (on behalf of Cochrane Clinical Answers Editors). Cochrane Clinical Answers 2021. DOI: 10.1002/cca.3469.
What is the accuracy of basal calcitonin for detection of medullary thyroid cancer in people with nodular thyroid disease? Jane Burch (PhD) and Adarsh Gupta (DO, MS, FACOFP) (on behalf of Cochrane Clinical Answers Editors). Cochrane Clinical Answers 2020. DOI: 10.1002/cca.3232.
Lyons P, Kennedy A, Clover AJP. Electrochemotherapy and basal cell carcinomas: First-time appraisal of the efficacy of electrochemotherapy on survivorship using FACE-Q. JPRAS Open. 2020 Dec 25;27:119-128. doi: 10.1016/j.jpra.2020.12.004. PMID: 33490356; PMCID: PMC7809247.
Fleming C, O'Keeffe S, McDermott R, Dunne M, McClean B, León Vintró L. The influence of Acuros XB on dose volume histogram metrics and tumour control probability modelling in locally advanced non-small cell lung cancer. Phys Med. 2020 Dec 19:S1120-1797(20)30305-7. doi: 10.1016/j.ejmp.2020.11.030. Epub ahead of print. PMID: 33349542.
Collins PM, Brennan MJ, Elliott JA, Abd Elwahab S, Barry K, Sweeney K, Malone C, Lowery A, Mclaughlin R, Kerin MJ. Neoadjuvant chemotherapy for luminal a breast cancer: Factors predictive of histopathologic response and oncologic outcome. Am J Surg. 2020 Dec 9:S0002-9610(20)30776-5. doi: 10.1016/j.amjsurg.2020.11.053. Epub ahead of print. PMID: 33334569.
Brady L, Hayes B, Sheill G, Baird AM, Guinan E, Stanfill B, Vlajnic T, Casey O, Murphy V, Greene J, Allott EH, Hussey J, Cahill F, Van Hemelrijck M, Peat N, Mucci L, Cunningham M, Grogan L, Lynch T, Manecksha RP, McCaffrey J, O'Donnell D, Sheils O, O'Leary J, Rudman S, McDermott R, Finn S. Platelet cloaking of circulating tumour cells in patients with metastatic prostate cancer: Results from ExPeCT, a randomised controlled trial. PLoS One. 2020 Dec 18;15(12):e0243928. doi: 10.1371/journal.pone.0243928. PMID: 33338056; PMCID: PMC7748139.
Saab MM, Noonan B, Kilty C, FitzGerald S, Collins A, Lyng Á, Kennedy U, O'Brien M, Hegarty J. Awareness and help-seeking for early signs and symptoms of lung cancer: A qualitative study with high-risk individuals. Eur J Oncol Nurs. 2020 Nov 24;50:101880. doi: 10.1016/j.ejon.2020.101880. Epub ahead of print. PMID: 33333451.
The Irish Cancer Society is currently accepting applications to its Social, Nursing and Allied Health Research Scholarship 2021.
The objective of this scholarship is to offer excellent social, nursing and allied health sciences graduates the opportunity to undertake postgraduate training in cancer research.
A number of changes have been made for the 2021 Social, Nursing, and Allied Health Research Scholarship:
· The Mobility Element has been adapted in recognition that extended travel is not always possible. It has been replaced with a Mobility and Capacity Building Element. Further details can be
· Part-time PhDs are now available for nursing and allied health applicants who will hold a concurrent clinical post during the course of the PhD
· Nursing and allied health professionals who will be taking time away from their professional clinical role may apply for a stipend in line with IUA rates and inclusive of PRSI and employer pension contributions.
Applications can be made through the Irish Cancer Society Gateway Grant Tracker online system. Further information about our open calls, including application guidelines, can be found here: https://www.cancer.ie/cancer-
The deadline for applications is 3pm Wednesday 03 March 2021.
Brown T, Cruickshank S, Noblet M. Specialist breast care nurses for support of women with breast cancer. Cochrane Database of Systematic Reviews 2021, Issue 1. Art. No.: CD005634. DOI: 10.1002/14651858.CD005634.pub3. Accessed 03 February 2021.
Aue-aungkul A, Kietpeerakool C, Rattanakanokchai S, Galaal K, Temtanakitpaisan T, Ngamjarus C, Lumbiganon P. Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage cervical cancer. Cochrane Database of Systematic Reviews 2021, Issue 1. Art. No.: CD012863. DOI: 10.1002/14651858.CD012863.pub2. Accessed 03 February 2021.
Njoku K, O'Flynn H, Jones E, Ramchander NC, White H, Macey R, Crosbie EJ. Screening tests for endometrial cancer in the general population. Cochrane Database of Systematic Reviews 2021, Issue 1. Art. No.: CD013859. DOI: 10.1002/14651858.CD013859. Accessed 03 February 2021. Diagnostic - Protocol
Rocco N, Catanuto G, Chiodini P, Rispoli C, Nava MB. Implants versus autologous tissue flaps for breast reconstruction following mastectomy. Cochrane Database of Systematic Reviews 2021, Issue 1. Art. No.: CD013821. DOI: 10.1002/14651858.CD013821. Accessed 03 February 2021. Intervention- Protocol
This guide was created to signpost online resources that are relevant to cancer care. Most resources included in this libguide are available from the National Health Library and Knowledge Service (NHLKS) via www.hselibrary.ie.
HSE staff need to register with their local HSE library and set up an OpenAthens account to access HSE library resources. Other resources available from this libguide are freely available (open access) and do not require a subscription.
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Access to online library resources available to HSE staff.
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