Cancer Care: Home

Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically focused entry point to rigorous research from Cochrane Reviews. They are designed to be actionable and to inform point of care decision making. 

Below are recent cancer related Cochrane clinical questions, click on the links to view answers. 

Do automated telephone communication systems (ATCSs) improve cancer screening rates? 17 December 2020

What are the effects of adjuvant progestogens for women with endometrial cancer? 17 December 2020.  

For adults with suspicious skin lesions, can smart phone applications (apps) accurately rule out cutaneous invasive melanoma and atypical intraepidermal melanocytic variants? 7 December 2020.  

How does radical prostatectomy compare with deferred treatment for people with localized prostate cancer?  24 November 2020.  

Fleming C, O'Keeffe S, McDermott R, Dunne M, McClean B, León Vintró L. The influence of Acuros XB on dose volume histogram metrics and tumour control probability modelling in locally advanced non-small cell lung cancer. Phys Med. 2020 Dec 19:S1120-1797(20)30305-7. doi: 10.1016/j.ejmp.2020.11.030. Epub ahead of print. PMID: 33349542.

Collins PM, Brennan MJ, Elliott JA, Abd Elwahab S, Barry K, Sweeney K, Malone C, Lowery A, Mclaughlin R, Kerin MJ. Neoadjuvant chemotherapy for luminal a breast cancer: Factors predictive of histopathologic response and oncologic outcome. Am J Surg. 2020 Dec 9:S0002-9610(20)30776-5. doi: 10.1016/j.amjsurg.2020.11.053. Epub ahead of print. PMID: 33334569.

Saab MM, Noonan B, Kilty C, FitzGerald S, Collins A, Lyng Á, Kennedy U, O'Brien M, Hegarty J. Awareness and help-seeking for early signs and symptoms of lung cancer: A qualitative study with high-risk individuals. Eur J Oncol Nurs. 2020 Nov 24;50:101880. doi: 10.1016/j.ejon.2020.101880. Epub ahead of print. PMID: 33333451.

McDermott RL, Mihai A, Dunne M, Keys M, O'Sullivan S, Thirion P, ElBeltagi N, Armstrong JG. Stereotactic Ablative Radiation Therapy for Large (≥5 cm) Non-small Cell Lung Carcinoma. Clin Oncol (R Coll Radiol). 2020 Dec 10:S0936-6555(20)30440-4. doi: 10.1016/j.clon.2020.11.026. Epub ahead of print. PMID: 33309479.

O'Dwyer N, Olden K, Cubbin AJ, Hill P, Flavin A, Rock K. Subungal squamous cell carcinoma of the thumb - Implications for patient setup and radiotherapy planning. Tech Innov Patient Support Radiat Oncol. 2020 Dec 3;16:83-86. doi: 10.1016/j.tipsro.2020.11.001. PMID: 33319076; PMCID: PMC7724189.

Tonry C, Finn S, Armstrong J, Pennington SR. Clinical proteomics for prostate cancer: understanding prostate cancer pathology and protein biomarkers for improved disease management. Clin Proteomics. 2020 Nov 20;17(1):41. doi: 10.1186/s12014-020-09305-7. PMID: 33292167; PMCID: PMC7678104.

Moloney C, Allen M, Power DG, Bambury R, O'Reilly S, O'Donnell DM, O'Mahony D, Collins DC. Assessing the quality of care delivered to transgender and gender diverse cancer patients in Ireland; a case series. Oncologist. 2020 Nov 30. doi: 10.1002/onco.13618. Epub ahead of print. PMID: 33252154.

O'Brien MMC, McLoughlin JM, Mulkerrin EC. Opportunistic Diagnosis of Extensive Pulmonary Embolus Following "COVID-19 Blood Battery" in Very Frail Older Patients. J Nutr Health Aging. 2020;24(10):1116-1119. doi: 10.1007/s12603-020-1450-0. PMID: 33244570; PMCID: PMC7403184.

New NCCP Guidelines were published in December 2020. 

Diagnosis, staging and treatment of patients with rectal cancer National Clinical Guideline No. 25

Diagnosis, staging and treatment of patients with colon cancer National Clinical Guideline No. 24

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